Columbia University Medical Center Research

The Babies Heart Fund helps to save and improve the lives of babies and adolescents with congenital heart disease (CHD). We have the largest pediatric heart transplant program in the country and perform over 700 surgeries per year. We are ranked within the top 5 Centers by volume and within the top 3 by outcomes. Our program is steadily decreasing the need for a child to endure multiple surgeries throughout their lifetime.

Congenital heart defects are the most common type of birth defect in the United States, affecting roughly 40,000 newborns per year.

The Babies Heart Fund is devoted to supporting vital research initiatives that will allow all children suffering from heart disease to grow up to be heart-healthy, strong adults. Our group plays a pivotal role in making this life-saving research not only possible, but attainable, by supporting our current research projects.

 

 

Brett Anderson, M.D., M.B.A. Assistant Professor of Pediatrics Columbia University Medical Center Attending Physician NewYork-Presbyterian/Morgan Stanley Children's Hospital

Brett Anderson, M.D., M.B.A.
Assistant Professor of Pediatrics
Columbia University Medical Center
Attending Physician
NewYork-Presbyterian/Morgan Stanley Children’s Hospital

Dr. Anderson conducts research on hypoplastic left heart syndrome (HLHS) and how to make the management of pediatric heart disease more cost-effective. She is using The Pediatric Health Information Systems Database — a national administrative database — to identify drivers of costs and cost-efficiency in order to develop means of reducing the costs of care for children with HLHS, while preserving or improving the quality of outcomes.

 

 

anjali-chelliah

Anjali Chelliah, M.D.
Assistant Professor of Pediatrics
Columbia University Medical Center

Dr. Chelliah specializes in non-invasive cardiac imaging, including echocardiography, fetal cardiology, cardiac magnetic resonance imaging, and cardiac computed tomography. Her research interests include using 3D printing to guide CHD surgery, minimizing radiation exposure in children with CHD, and using fetal and pediatric echocardiography to predict and improve clinical outcomes.

 

 

 

 

matt-crystal

Matthew Crystal, M.D.
Assistant Professor of Pediatrics
Columbia University Medical Center
Attending Physician
NewYork-Presbyterian/Morgan Stanley Children’s Hospital

Dr. Crystal is an expert in fetal cardiac intervention, which involves performing surgery on fetuses so that their heart defects can be partly or totally repaired before they are born. His pioneering research seeks to develop non-surgical therapies for congenital heart disease, while establishing the safest interventions for our youngest patients: those still in the womb. He also pursues modalities for children undergoing cardiac catheterization and intervention with device implantation, in the hopes of improving clinical outcomes for children with pulmonary vein stenosis.

 

 

teresa-lee

Teresa Lee, M.D.
Assistant Professor of Pediatrics
Columbia University Medical Center
Attending Physician
NewYork-Presbyterian/Morgan Stanley Children’s Hospital

Dr. Lee is conducting trailblazing stem cell research in congenital heart disease, in which she studies how causal genetic mutations manifest in the heart at the cellular level. She developed a new technique to study a patient’s heart cells in a petri dish to investigate why the muscle is not working as it should. (This includes the process of reprogramming fibroblasts to become induced pluripotent stem cells that can then be converted into any other cell type.) Through greater understanding from this research of precisely what goes wrong with the heart cells, doctors and researchers will have a better roadmap for optimally treating each patient’s unique heart defect.

 

 

anna-joong

Anna Joong, M.D.
Pediatric Cardiology Chief Fellow
Columbia University Medical Center

Dr. Joong conducts research on pediatric heart failure and transplant-induced cardiomyopathies (in which the heart muscle deteriorates). She is also working with pediatric hematology-oncology to provide a cardiology presence in their outpatient clinics so that our heart failure team will see all patients pre- and post-chemotherapy to assess for and treat any chemo-induced heart failure.

 

 

 

Kimara L. Targoff, M.D.
Assistant Professor of Pediatrics
Columbia University Medical Center

Dr. Targoff’s research is focused on determining how specific genes can be used to stimulate the regeneration process. The genes and molecules that govern cardiac development could be manipulated to transform stem cells into new heart muscle for replacement in adults with heart disease and in children born with heart defects. This approach could also aid in the discovery and testing of new drugs for heart patients.

View a short video about Dr. Targoff’s important research: https://www.youtube.com/embed/NcjpCatwrSk

 

 

 

While our doctors have made great strides, we are still some years away from fully realizing our goal. With the help of philanthropy, we hope to have the resources necessary for all children to live in a world free of heart disease.

Our mission is to lead the world in curing congenital heart disease
One gene…
One cell…
One heart at a time!

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